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Research/Earlier Research

Generative models
for microbiome data.

Research experience in Professor Li Ma’s group at Duke University.

Group
Professor Li Ma, Department of Statistical Science, Duke
Period
May – Dec 2024
Data
American Gut dataset
Role
Collaborative research
Schematic: observed and generated microbiome compositions; not data.Schematic · not data
Question

What does a generated sample preserve?

A generative model can produce samples that look plausible. The harder question is whether they keep what matters for the analyses people run on real microbiome data.

What I did

Models, compared at scale.

I studied different generative models and neural networks on their ability to generate microbiome data, with an emphasis on generating large datasets, and ran the work on large computing clusters using the American Gut dataset.

How it was judged

By downstream analyses.

The quality of generated data was evaluated with bioinformatics analyses, using R packages for microbiome data.

Limits

What this page does not show.

  • No results are shown here.
  • The figure is a schematic of observed and generated compositions, not data.